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To further explore the association of ASXL1 and BRD4 in the cellular context, we performed chromatin immunoprecipitation coupled with deep sequencing (ChIP-seq) of endogenous ASXL1, BRD4 and BAP1 and assessed genomic occupancies of these proteins in human HEK293T cells

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Similarly, the ELF score, which combines serum markers of matrix turnover including hyaluronic acid, procollagen type III n-terminal peptide (PIIINP), and tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) has been validated for fibrosis staging and is currently recommended by several guidelines [79, 80]

Deformability Optimization: Integrating biocompatible edge activators to lower the elastic modulus of the membrane, enabling the vesicles to physically squeeze through the stratum corneum via intercellular pathways

Identification of the -glutamyl cycle as a novel therapeutic target and 5-oxoproline as a new biomarker for diagnosing pancreatic cancer